Top 5 HIV cure and vaccine stories from AIDS 2020

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Top 5 HIV cure and vaccine stories from AIDS 2020
The recent 23rd International AIDS Society conference, also known as AIDS 2020, presented the latest research towards the development of an HIV cure and vaccine.

A Brazilian man who has spent 15 months off antiretrovirals without, so far, HIV being detected in any test may represent the first case of a functional cure without the risks of a stem cell transplant. However, experts caution against reading too much into this case, as it involved only a single individual and extensive testing for traces of HIV at various sites in the man's body have not yet been carried out. Our coverage includes a video interview with Dr Andrea Savarino, one of the scientists involved, as well as a commentary by NAM’s Gus Cairns, who asks whether someone has just been cured of HIV with a cheap, simple drug regimen?

Leading researchers debated whether gene therapy or immunotherapy is more likely to lead to an HIV cure. We have proof of concept for a gene therapy approach in the cases of two men who have been cured following stem cell transplants from donors with a mutation in the gene for CCR5. However, some experts believe that an immune therapy approach is more likely to deliver long-term remission of HIV and could be delivered at scale, noting that immunotherapies are already being used to treat cancers.
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