Top 10 Pharmaceutical companies (1998-2020) - Ranking History Trends !

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The global pharmaceutical industry reached unprecedented heights in 2018, being estimated at an astounding $1.11 trillion. By 2020, this figure is set to rise to $1.43 trillion. With rising pressure to develop drugs to meet ever increasing global demand, pharmaceutical companies continue to work tirelessly to bring the most innovative and cutting-edge treatments to patients.

Being a research-driven industry, approximately $150 billion is spent by pharmaceutical companies every year on research and development projects. Out of thousands of compounds, only a small percentage gain regulatory approval to be used by patients to treat disease and improve quality of life. However, in 2018, a record number of novel drugs developed by pharmaceutical companies across the globe were approved by various regulatory bodies. A large proportion were approved by the US regulatory body, the FDA, which approved 55 novel drugs and smashed its record for generic approvals (781 up from 763 in 2017).

Although the USA’s market share of the global pharmaceutical industry is worth over $341.1 billion, the Chinese, South East Asian, Eastern European and South American markets are beginning to emerge. For example, the Chinese market is rich with preclinical and early-phase drugs, and is a growing nucleus of biotech activity. The next few years will see global growth thanks to the increasing wealth worldwide, as well as increasing demand to maintain high levels of innovation to combat unmet medical need.


Bristol-Myers Squibb (BMS)
US $22.6 billion

A new entry into the top 10 pharma list is Bristol-Myers Squibb, a leading American pharmaceutical company headquartered in New York City. BMS specialises in four key therapy areas: oncology, cardiovascular, immunoscience and fibrosis. The company's strong growth in 2018 can be in part attributed to continued success of leading drugs Opdivo (cancer) and Eliquis (a blood thinner). BMS' success is likely to be further boosted following the company's planned acquisiton of Celgene - an innovative oncology biotech - in early 2019. This strategic acquisition will help position BMS as a leading biopharma player thanks to Celgene's robust pipeline.




GlaxoSmithKline (GSK)
US $23 billion

A staple candidate in the top 10 pharma list year on year, GlaxoSmithKline (GSK) is a leading British pharmaceutical company that always boasts a strong pipeline of innovative drugs. The company specialises in a broad range of therapy areas but is particularly successful in the fields of HIV/AIDS, respiratory and vaccines. The company enjoyed 2% revenue growth compared with 2017 figures, with sales being boosted by GSK’s best-selling HIV drugs Trivicay and Triumeq, the Ellipta inhaler for asthma and COPD and Nucala, another successful asthma treatment. Last year GSK saw the key approval of Shingrix, developed to treat the shingles virus, which was very successful in 2018 as expected, with sales reaching £784 million. In general, growth was slightly offset by steep generic competition in 2018 for various GSK drugs like Seretide, Epizixom and Avodart.




Amgen
US $23.7 billion

Amgen is an American biopharmaceutical company headquartered in California that specialises in developing novel human therapeutics, with a focus on cardiovascular disease, oncology, bone health, neuroscience, nephrology, and inflammation. The company is steadily becoming a permanent fixture on this top 10 list. This change is in part due to the success of various Amgen products, including Repatha (72% increase yoy), BLINCYTO® (31% increase yoy) and Prolia® (16% increase yoy). In early 2019, Amgen was voted one of Fortune Magazine’s Most Admired Companies in the pharmaceutical industry and was listed number 5 on Fast Company's 2019 Most Innovative companies.



AbbVie
US $32.8 billion

Research-driven American biopharma AbbVie has maintained its position on this list, with an impressive increase of 16.2% compared with 2017 pharma revenue statistics. AbbVie has recently announced that upadacitinib, one of their most anticipated drugs in development that will be used to treat moderate to severe atopic dermatitis, has been granted breakthrough therapy designation by the FDA.



Novartis
US $34.9 billion


Merck & Co
US $37.7 billion

Sanofi
US $39.3 billion


Johnson & Johnson
US $40.7 billion

In the top 3 pharmaceutical companies in the world is Johnson & Johnson, a company that was established over 130 years ago and has become a staple household name thanks to popular consumer goods like Aveeno, Neutrogena and Listerine.


Roche
US $45.6 billion

Pfizer
US $53.7 billion